Clinical applications

Evidence should arrive where the clinical trajectory changes.

REACT is developing two explainable, AI-supported dashboards: one for responsible antibiotic use and one for early recognition of circulatory instability. Clinical judgement and responsibility remain with the treating clinicians.

REACT / clinician-facing evidence

Two decision contexts. One governed evidence pathway.

Development and retrospective evaluation draw on around 200,000 ICU stays. A non-interventional pilot at Charité and University Medicine Essen is planned after the project to explore use in clinical workflows and inform possible later regulatory approval and sustained clinical use.

Clinical demonstrator

Antimicrobial stewardship

The dashboard is designed to assess guideline adherence and help teams consider antibiotic de-escalation and therapy adjustment, with explanations grounded in patient context.

guideline adherencede-escalationtherapy durationmicrobiology context
Clinical demonstrator

Hemodynamic trajectories

Learning models are being developed to highlight early warning signs of circulatory instability. The dashboard will show the signals behind each assessment to support clinical judgement.

blood pressure trajectoryvasopressor trendlactate kineticsperfusion context
Clinical research team discussing ICU trajectory data
REACT / clinical translation

Publications / clinical applications

Clinical findings and demonstrator reports will be listed here.

This space will collect publications, evaluation reports and implementation artefacts from the antimicrobial-stewardship and hemodynamic workstreams.

Publications coming soonREACT / 2026